Related titles	<< BACK
	Approaches to Gene Mapping in Complex Human Diseases Edited by J.L. HAINES, Vanderbilt University and M.A. PERICAK-VANCE, Duke University Medical Center, USA The first book to be devoted to the analysis of common, inherited diseases. This text helps the reader sort through the plethora of available resources, choose the best methodology for the given problem, and design successful gene mapping projects from the ground up. Clearly explains concepts and design procedures while keeping technical details to a minimum Provides both a solid grounding in the fundamentals and a firm grasp of the most advanced procedures and techniques available. Covers a wide range of topics - from the process of selecting families to the testing of candidate genes.
Contents: Overview of Mapping Common and Genetically Complex Human Disease Traits Basic Concepts in Genetics Defining Disease Phenotypes Basic Concepts in Linkage Analysis Determining the Genetic Component of a Disease Patient and Family Participation in Genetic Research Studies Sample Size and Power The College of Biological Samples for DNA Analysis Methods of Genotyping Database Design for Gene Mapping Studies Genomic Screening Lod Score Analysis Sib Pair Analysis Affected-Relative-Pair Methods of Analysis Linkage Disequilibrium and Allelic Association Using Public Databases Laboratory Approaches Toward Gene Identification Examining Complex Genetic Interactions 0471 17195 6456 ppNovember 1998Hardback
Home | Feedback | About Wiley © John Wiley & Sons Ltd, 1999.    (Best viewed with Navigator 4 or MSIE 4 and 16bit colour)