TABLE OF CONTENTS
EPIDEMIOLOGY & DIAGNOSIS
Section Editor: Peter H. Bennett, Senior Investigator, Phoenix Epidemiology
and Clinical Research Branch, NIDDK, Phoenix, Arizona, USA
PROVISIONAL CONTENTS
Classification of DM
and other categories of glucose intolerance
Paul Zimmett and Catherine C Cowie, International Diabetes Institute, Caulfield
Victoria, Australia
Epidemiology and geography
of type 1 Diabetes Mellitus
Marian Rewers and Andrea Steck, University of Colorado, Denver, USA
Epidemiology and geography
of type 2 Diabetes Mellitus in Europids and non-Europids
Jaakko Tuomilehto and Qing Qiao, National Public Health Institute, Mannerheimintie,
Finland

NORMAL PHYSIOLOGY OF
PANCREATIC FUNCTION
Section Editor: Erol Cerasi, Professor, Endocrinology and Metabolism,
Hadassah Medical Center, Jerusalem, Israel
Development and life-cycle
of a beta-cell
P Serup, University of Copenhagen, Copenhagen, Denmark and J. H. Nielsen, Hagedorn
Research Laboratory, Gentofte, Denmark
Morphology of the pancreas
in normal and diabetic states
Anne Clark, Diabetes Research Laboratory, Radcliffe Infirmary, Oxford, UK
Insulin gene expression
and biosynthesis of proinsulin
Ronald Stein, Vanderbilt Medical Cente, Department of Molecular Physiology &
Biophysics, Nashville, TN, USA
Beta-cell biology of
insulin secretion
Claes B Wollheim and Pierre Maechler, Division of Biochemistry, University Medical
Centre, Geneva, Switzerland
Assessment of insulin
secretion in Man and insulin secretion in healthy subjects (including role
of Incretins)
Author to be confirmed
Neuropeptides and insulin
secretion
Bo Ahren, Department of Medicine, Lund University, Lund, Sweden
Biological effects of
proinsulin and C-peptide
John Wahren, Department of Clinical Physiology, Karolinska Hospital, Stockholm,
Sweden
Assays for insulin and
precursors
Author to be confirmed
Biosynthesis, secretion
and action of glucagon
Pierre Lefèbvre, Départment de Médecine, Université
du Sart Tilman, Liège Belgium
Islet amyloid polypeptide/GLP-1/Exendin
L. Baggio, Daniel Ducker and Bob McArthur, Banting & Best Diabetes Centre,
University of Toronto, Toronto, Canada

NORMAL PHYSIOLOGY OF
INSULIN ACTION
Section Editor: W. Timothy Garvey, Professor, Department of Medicine, Medical
University of South Carolina, Charleston, USA
PROVISIONAL CONTENTS
Molecular basis of insulin
action: Acute metabolic signalling
Author to be confirmed
Regulation of intracellular
glucose metabolism
Author to be confirmed
The assessment of insulin
action in vivo
Richard N Bergman, USC Keck School of Medicine, Los Angeles, USA
Insulin regulation of
in vivo glucose metabolism
Ele Ferrannini, University of Pisa School of Medicine, Pisa, Italy and Ralph
A. DeFronzo, The University of Texas Health Science Center at San Antonio, San
Antonio, USA
Insulin regulation of
protein metabolism
Eugene Barrett and Zhenqi Liu, University of Virginia School of Medicine, Charlottesville,
VA, USA
Lipid and lipoprotein
metabolism
Barbara V. Howard and Giacomo Ruotolo, Medstar Research Institute, Washington
DC, USA
Insulin regulation of
ketone body metabolism
Robert R. Henry, Theodore P. Ciaraldi and Sunder Mudaliar, University of California
San Diego School of Medicine, San Diego, CA, USA
Genetic basis of diabetes
Braxton Mitchell and Alun Shuldiner, University of Maryland School of Medicine,
Baltimore, MD, USA

PATHOGENESIS
Section Editor: Hannele Yki-Jarvinen, Professor, Department of Medicine,
University of Helsinki, Helsinki, Finland
Pathogenesis of abnormal
glucose metabolism in type 2 diabetes
Ralph A DeFronzo, The University of Texas Health Science Center at San Antonio,
7703 Floyd Curl Drive, San Antonio, USA
Molecular genetics of
type 2 diabetes
Leif Groop, Department of Endocrinology, Wallenberg Laboratory, University Hospital,
Lund, Sweden
Molecular mechanisms of insulin resistance in type 2 diabetes
Author to be confirmed
Abnormalities in insulin
secretion in type 2 diabetes
Author to be confirmed
Glucose toxicity
Hannele Yki-Jarvinen, Department of Medicine, University of Helsinki, Helsinki,
Finland
Monogenic beta-cell dysfunction
Andrew Hattersley and E. R. Pearson, Department of Diabetes and Vascular Medicine,
School of Postgraduate Medicine, Barrack Road, Exeter, UK
Immunopathogenesis of
type 1 diabetes in Western society
George Eisenbarth and Johanna Paronen, Barbara Davis Center, Denver, USA
Diabetes secondary to
acquired disease of the pancreas
Author to be confirmed
Molecular genetics of
type 1 diabetes
Author to be confirmed
The Insulin Resistance
Syndrome
Author to be confirmed

OBESITY
Section Editor: Eric Ravussin, Professor, Pennington Biomedical Research
Center, Los Angeles, USA
The relationship between
obesity and type 2 diabetes
Per Bjorntorp, University of Göteborg, Göteborg, Sweden
Genetics of obesity
Claude Bouchard, Pennington Biomedical Research Center, Los Angeles, USA
Role of adipocyte in
type 2 diabetes
Stephen Farmer, Department of Biochemistry, Boston University School of Medicine,
715 Albany Street, Boston, MA, USA
Animal models of obesity
D. A. York, Pennington Biomedical Research Center, Los Angeles, USA
The role of the hypothalamus
in the maintenance of energy balance and peripheral glucose control
Deborah J Clegg, Michael W Schwartz, Stephen C Woods and Randy J. Seeley, University
of Cincinnati, Cincinnati, OH, USA
Michael W Schwartz, Habourview Medical Center and University of Washington,
Seattle, WA, USA
Regulation of the energy
balance
Ralph Underwood, Pennington Biomedical Research Center, Baton Rouge, USA
Eric Ravussin, Pennington Biomedical Research Center, Los Angeles, USA
Is type 2 diabetes the
result of a "thrifty genotype" or a "thrifty phenotype"?
Robert S. Lindsey, National Institutes of Health, Phoenix, Arizona, USA
Treatment of obesity
Arne Astrup, Research Department of Human Nutrition, The Royal Veterinary and
Agricultural University, Frederiksberg, Denmark
Lipodystrophies and diabetes
Abhimanyu Garg, University of Texas Southwestern Medical Center at Dallas, Dallas,
Texas, USA

MANAGEMENT OF DIABETES
I: DIET AND DRUGS
Section Editor: Rury Holman, Professor, Diabetes Trials Unit, Radcliffe Infirmary,
Oxford, UK
PROVISIONAL CONTENTS
Dietary management of
Diabetes Mellitus in Europe and North America
Author to be confirmed
Dietary management of
Diabetes Mellitus in India and South East Asia
Author to be confirmed
Dietary management of
Diabetes Mellitus in Japan
Author to be confirmed
Dietary management of
Diabetes Mellitus in Africa
Author to be confirmed
Dietary management of
Diabetes Mellitus in China
Author to be confirmed
Dietary management of
Diabetes Mellitus in the Middle East
Author to be confirmed
Exercise
Author to be confirmed
Sulphonylureas: Basic
aspects and clinical uses
Author to be confirmed
Meglitimides: Basic aspects
and clinical uses
Author to be confirmed
Biguanides: Basic aspects
and clinical uses
Author to be confirmed
Thializlidinediones PPAR
agonists
Author to be confirmed
Alpha-glucosidase inhibitors
Author to be confirmed
Combination therapy
Author to be confirmed
New drugs for the treatment
of Diabetes Mellitus
Author to be confirmed
Hypolipidemic agents:
Their role in Diabetes Mellitus
Author to be confirmed
Insulin therapy
Author to be confirmed
Management of IGT/IFG
(liposome, alpha-glucosides etc.)
Author to be confirmed

MANAGEMENT OF DIABETES
II: MONITORING AND OTHER INTERVENTIONS
Section Editor: Bernard
Zinman MDCM FRCPC FACP, Director, Leadership Sinai Centre for Diabetes, Sam
and Judy Pencer Family Chair in Diabetes, Professor of Medicine, University
of Toronto, Samuel Lunenfeld Research Institute, Mont Sinai Hospital, 782-600
University Avenue, Toronto, Ontario M5G 1X5, Canada
Alternative routes for
insulin delivery
D. R. Owens, Llandough Hospital, Penarth, UK
Bernard Zinman, University of Toronto, Toronto, Canada
G. Bolli, University of Perugia, Perguia, Italy
Implantable pumps
Chee W. Chia and Chris D Saudek, John Hopkins Hospital, Baltimore, USA
Artificial and bio-artificial
pancreas systems
Author to be confirmed
Complications of insulin
therapy
S. Edwin Fineberg and James H. Anderson, Indiana University School of Medicine,
Indianopolis, USA
Islet transplantation
Author to be confirmed
Pancreas transplantation
Paul Robertson, Pacific Northwest Research Institute, Seattle, Washington, USA
Hypoglycaemia
Philip E Cryer, Washington University School of Medicine, St Louis, MO, USA
Brian M. Frier, The Royal Infirmary, Edinburgh, UK
Diabetic ketoacidosis
and Hyperglycaemia Hyperosmolar state
Abbas E Kitabchi, Mary
Elizabeth Murphy and Guilermo Umpierrez, University of Memphis, Memphis, TN,
USA

MANAGEMENT OF DIABETES
III
PROVISIONAL CONTENTS
Education of the diabetic
patient
Author to be confirmed
Computer-assisted diabetes
education
Author to be confirmed
Information technology
in diabetes care
Author to be confirmed
Monitoring diabetes with
urine tests
Author to be confirmed
Self-monitoring of blood
glucose
Author to be confirmed
Glycated hemoglobin and
serum proteins as tools for monitoring
Author to be confirmed
Monitoring of lipids
in diabetes
Author to be confirmed
Glucose sensors: Present
and future
Author to be confirmed
Diabetes in Childhood
and Adolescence
Author to be confirmed
Difficult diabetes
Author to be confirmed
Diabetes Mellitus, pregnancy
and gestational diabetes
Author to be confirmed
Aging and diabetes
Author to be confirmed
Psychological problems
and management of patients with diabetes mellitus
Author to be confirmed
Infections, immunity
and diabetes
Author to be confirmed
The care of the patient
during surgery
Author to be confirmed

COMPLICATIONS OF DIABETES
I: GENERAL AND MICROVASULAR
Section Editor: G. L. King, Professor, Joslin Diabetes Center, Boston,
MA, USA
PROVISIONAL CONTENTS
Complications of diabetes:
The changing scene
Author to be confirmed
Epidemiology of microvascular
complications
Author to be confirmed
Glycemic control and
the complications of diabetes
Author to be confirmed
Glycation
Author to be confirmed
The microcirculation
in Diabetes Mellitus
Author to be confirmed
The pathology and clinical
aspects of diabetic neuropathy
Author to be confirmed
Diabetic retinopathy
Author to be confirmed
Diabetic effects on non-retinal
ocular structures
Author to be confirmed
Visual impairment and
diabetes
Author to be confirmed
Diabetic peripheral neuropathy
and pathology
Author to be confirmed
Autonomic neuropathy
Author to be confirmed
Connective tissue disorders
in diabetes
Author to be confirmed
The diabetic foot
Author to be confirmed

COMPLICATIONS OF DIABETES
II: MACROVASCULAR
Section Editor: John S. Yudkin, Professor, Diabetes and Cardiovasular
Disease Academic Unit, Royal Free and University College Medical School, London,
UK
Atherogenesis and coronary
heart disease
Author to be confirmed
Epidemiology of macrovascular
disease and hypertension in diabetes
Author to be confirmed
Clinical features and
treatment of coronary heart disease in diabetes
Rosaire Gray and John Yudkin, Cardiovascular Department, Whittington Hospital,
London, UK
Glycaemic control and
macrovascular disease
William H Herman and Abdulaziz Alharthi, University of Michigan Medical Center,
Ann Arbour, MI, USA
Clinical features and
treatment of peripheral vascular disease in diabetes
Author to be confirmed
Arterial hypertension
in diabetes: Aetiology and treatment
Henry Black, George Bakris and Nauman Tarif, Luke's Medical Center, Chicago,
IL, USA
Clotting disorders in
diabetes
Irene Juhan-Vague, Haematology Depatment, CHU Timone, Marseille, FRANCE
Marie-Christine Alessi and R. E. Morange, CHU Timone, Marseille, France
Cerebrovascular disease
and diabetes
Christopher S Gray, University of Newcastle School of Clinical Medical Science,
Royal Hospital, Sunderland, UK
Insulin Resistance Syndrome
and its links to macrovascular disease
Riccardo Bonadonna, Divisione di Encrinologia e Malattie del Metabolismo, Ospedale
Civile Maggiore, Verona, ITALY
Endothelial function
and dysfunction
Coen A. Stehuower, Medical Centre, Vrije University, Amsterdam, The Netherlands
Biochemical aspects,
glycation and oxidative stress
Michael Brownlee, Albert Einstein College of Medicine, New York, USA and Jane
Reusch, University of Colarado, Colarado, USA

DIABETES AND PUBLIC HEALTH
Section Editor: John R. Turtle, Professor, Diabetes and Cardiovascular
Disease Academic Unit, Royal Free and University College Medical School, London,
UK
Screening for diabetes
and glucose intolerance
Sir George Alberti, Department of Medicine, University of Newcastle upon Tyne,
Newcastle, UK, Paul Zimmet and Johnathan Shaw, International Diabetes Institute,
Victoria, Australia and Gary Dowse, Department of Health, Communicable Disease
Control Branch, WA, Australia
Organisation of care:
the "at risk" person in the community
Karen Lam and Kathryn Tan, Professor, Department of Medicine, University of
Hong Kong, Hong Kong
Organisation of care:
Europe and the St Vincent Declaration
Author to be confirmed
Organisation of care:
USA community control programs
Author to be confirmed
Organisation of care:
The Western Pacific Region
Clive Cockram, Department of Medicine, The Prince of Wales Hospital, Shatin,
Hong Kong
Organisation of care:
Problems in developing countries - South East Asia
Samad Shera, Diabetic Association of Pakistan, Karachi, Pakistan
Organisation of care:
Problems in developing countries - Sub-Saharan Africa
Jean-Claude Mbanya, Endocrine and Diabetes Unit, Faculty of Medicine, University
of Yaounde, Cameroon
Organisation of care:
Problems in developing countries - South America
Julio Libman, Santa Fe, Argentina
Pablo Arias, Universidad de Buenos Aires, Argentina
Astrid M. Libman, Universidad de Rosario, Argentina
Organisation of care:
Diabetes community programmes
Author to be confirmed
Diabetic life problems:
Social rights
M Massi-Benedetti, University of Perugia, Perugia, Italy
The economics of diabetes
care: Europe
Rhys Williams and Kamran Siddiqi, Nuffield Institute of Health, University of
Leeds, Leeds, UK
The economics of diabetes
care: USA
Author to be confirmed
The economics of diabetes
care: Australia
Jane Overland, Diabetes Center, Royal Prince Alfred Hospital, NSW, Australia
The economics of diabetes
care: Africa
Author to be confirmed
The economics of diabetes
care: the Middle East
Morsi Arab, Department of Internal Medicine, University of Alexandria, Alexandria,
Egypt
The economics of diabetes
care: South East Asia
Clive Cockram, Department of Medicine, The Prince of Wales Hospital, Shatin,
Hong Kong
Prevention of type 1
diabetes
Len Harrison, The Walter and Eliza Hall Institute of Medical Research, Royal
Melbourne Hospital, Victoria, Australia
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